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PXD052910

PXD052910 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDiscovery and development of CLL-1 as a cellular immunotherapy target in juvenile myelomonocytic leukemia
DescriptionJuvenile myelomonocytic leukemia (JMML) is an aggressive hematologic malignancy with myeloproliferative characteristics that affects young children and is associated with significant morbidity and mortality. Leukemia stem cells (LSCs) have been shown to drive relapse and progression in JMML and include Lin-CD34+CD38-/+ hematopoietic stem cells (HSCs)​14​. We therefore sought to develop cellular immunotherapy against JMML by employing a multi-modal omics strategy, focusing specifically on targeting chemoresistant LSCs
HostingRepositoryPRIDE
AnnounceDate2025-02-04
AnnouncementXMLSubmission_2025-02-04_02:34:24.547.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAbhilash Barpanda
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetic acid derivatized residue
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-06-06 16:27:28ID requested
12025-02-04 02:34:24announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: JMML, Surfaceomics, CAR-T cell, Immunotherapy
Contact List
Arun Wiita, Elliot Steglitz
contact affiliationAssociate Professor, Department of Laboratory Mediciene, UCSF
contact emailarun.wiita@ucsf.edu
lab head
Abhilash Barpanda
contact affiliationIIT Bombay
contact emailavilash94@iitb.ac.in
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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