PXD052910 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Discovery and development of CLL-1 as a cellular immunotherapy target in juvenile myelomonocytic leukemia |
Description | Juvenile myelomonocytic leukemia (JMML) is an aggressive hematologic malignancy with myeloproliferative characteristics that affects young children and is associated with significant morbidity and mortality. Leukemia stem cells (LSCs) have been shown to drive relapse and progression in JMML and include Lin-CD34+CD38-/+ hematopoietic stem cells (HSCs)14. We therefore sought to develop cellular immunotherapy against JMML by employing a multi-modal omics strategy, focusing specifically on targeting chemoresistant LSCs |
HostingRepository | PRIDE |
AnnounceDate | 2025-02-04 |
AnnouncementXML | Submission_2025-02-04_02:34:24.547.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Abhilash Barpanda |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetic acid derivatized residue |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-06-06 16:27:28 | ID requested | |
⏵ 1 | 2025-02-04 02:34:24 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: JMML, Surfaceomics, CAR-T cell, Immunotherapy |
Contact List
Arun Wiita, Elliot Steglitz |
contact affiliation | Associate Professor, Department of Laboratory Mediciene, UCSF |
contact email | arun.wiita@ucsf.edu |
lab head | |
Abhilash Barpanda |
contact affiliation | IIT Bombay |
contact email | avilash94@iitb.ac.in |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD052910 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD052910
- Label: PRIDE project
- Name: Discovery and development of CLL-1 as a cellular immunotherapy target in juvenile myelomonocytic leukemia