PXD052910

PXD052910 is an original dataset announced via ProteomeXchange.

Title	Discovery and development of CLL-1 as a cellular immunotherapy target in juvenile myelomonocytic leukemia
Description	Juvenile myelomonocytic leukemia (JMML) is an aggressive hematologic malignancy with myeloproliferative characteristics that affects young children and is associated with significant morbidity and mortality. Leukemia stem cells (LSCs) have been shown to drive relapse and progression in JMML and include Lin-CD34+CD38-/+ hematopoietic stem cells (HSCs)​14​. We therefore sought to develop cellular immunotherapy against JMML by employing a multi-modal omics strategy, focusing specifically on targeting chemoresistant LSCs
HostingRepository	PRIDE
AnnounceDate	2025-02-04
AnnouncementXML	Submission_2025-02-04_02:34:24.547.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Abhilash Barpanda
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetic acid derivatized residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-06 16:27:28	ID requested
⏵ 1	2025-02-04 02:34:24	announced

Dataset with its publication pending

submitter keyword: JMML, Surfaceomics, CAR-T cell, Immunotherapy

Arun Wiita, Elliot Steglitz
contact affiliation	Associate Professor, Department of Laboratory Mediciene, UCSF
contact email	arun.wiita@ucsf.edu
lab head
Abhilash Barpanda
contact affiliation	IIT Bombay
contact email	avilash94@iitb.ac.in
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD052910

PRIDE project URI

• PRIDE
  1. PXD052910
     1. Label: PRIDE project
     2. Name: Discovery and development of CLL-1 as a cellular immunotherapy target in juvenile myelomonocytic leukemia