<<< Full experiment listing

PXD052863

PXD052863 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCharacterisation of reproductive tract microbiome and immune biomarkers for Bovine Genital Campylobacteriosis in vaccinated and unvaccinated heifers
DescriptionBovine genital campylobacteriosis (BGC) is a globally important venereal disease of cattle caused by Campylobacter fetus subspecies (C. fetus) venerealis. Diagnosis of BGC is highly challenging due to the lack of accurate diagnostic tests. To characterise the immune biomarkers for C. fetus venerealis infection, a total of twelve six cycling heifers were selected and categorised as vaccinated (n=6) with Vibrovax® (Zoetis™) and unvaccinated (n=6). All heifers were oestrous synchronised with a double dose of prostaglandin (PGF2) 11 days apart and when in oestrous intravaginally challenged with 2.7x109 CFU live C. fetus venerealis. Relative abundances of serum proteins were calculated using sequential window acquisition of all theoretical fragment ion spectra coupled to tandem mass spectrometry (SWATH-MS) for all heifers at three timepoints: pre-challenge, post-challenge and post-recovery.
HostingRepositoryPRIDE
AnnounceDate2024-10-17
AnnouncementXMLSubmission_2024-10-17_05:27:42.313.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAli Raza
SpeciesList scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationListNo PTMs are included in the dataset
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-06-05 08:50:16ID requested
12024-10-17 05:27:43announced
Publication List
10.3389/fmicb.2024.1404525;
Juli MSB, Raza A, Forutan M, Siddle HV, Fordyce G, Muller J, Boe-Hansen GB, Tabor AE, Characterisation of reproductive tract microbiome and immune biomarkers for bovine genital campylobacteriosis in vaccinated and unvaccinated heifers. Front Microbiol, 15():1404525(2024) [pubmed]
Keyword List
submitter keyword: Biomarker, Reproductive, Microbiome, Venereal disease, BGC, Proteomics, Cattle
Contact List
Ala Tabor
contact affiliationQueensland Alliance for Agriculture and Food Innovation, University of Queensland
contact emaila.tabor@uq.edu.au
lab head
Ali Raza
contact affiliationUniversity of Queensland
contact emaila.raza@uq.edu.au
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/10/PXD052863
PRIDE project URI
Repository Record List
[ + ]