<<< Full experiment listing

PXD052816

PXD052816 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleFull transcriptome and proteome analysis of the mechanism of tuberculosis Ag85B-Fc2a in alleviating allergic asthma in mice
DescriptionIn the early stage, an OVA-induced mouse allergic asthma model was constructed and treated with Ag85B-Fc2a fusion protein, which proved that Ag85B-Fc2a fusion protein could reduce the infiltration of inflammatory cells in the lungs and had a therapeutic effect on asthma怂In order to further explore the mechanism of action, we carried out transcriptomics and proteomic sequencing, screened out related genes and proteins, enriched them, and focused on pathways with significant differences. In the later stage, q-PCR and Western-blot experiments will be performed for verification.
HostingRepositoryiProX
AnnounceDate2024-06-04
AnnouncementXMLSubmission_2024-06-03_23:50:56.356.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterTiansong Wang
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-06-03 23:50:19ID requested
12024-06-03 23:50:56announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Ag85B-Fc2a, transcriptome, proteome analysis
Contact List
Qiaofeng Wan
contact affiliationNingxia Medical University
contact emailwqiaofeng@126.com
lab head
Tiansong Wang
contact affiliationNingxia Medical University
contact emailshanyanghaoranqi@126.com
dataset submitter
Full Dataset Link List
iProX dataset URI