PXD052742

PXD052742 is an original dataset announced via ProteomeXchange.

Title	Quantative pTyr protein complex
Description	Our current research focuses on the complex-centric quantification of pTyr protein complexes. We initially constructed a tri-functional probe based on pTyr superbinder (SH2-S) for the enrichment of pTyr protein complexes. The pTyr protein complexes were separated by ion exchange chromatography (IEC). To further quantify the complexes, we developed an algorithm for co-fractionation/mass spectrometry (CF/MS) protein complex screening and quantification.
HostingRepository	iProX
AnnounceDate	2024-05-31
AnnouncementXML	Submission_2025-03-11_19:12:03.018.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wei Liu
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-05-30 20:36:34	ID requested
⏵ 1	2025-03-11 19:12:03	announced

Liu W, Wang X, Yu H, Yan G, Shen S, Gao M, Zhang X, Integrated Platform for Large-Scale Quantitative Profiling of Phosphotyrosine Signaling Complexes Based on Cofractionation/Mass Spectrometry and Complex-Centric Algorithm. Anal Chem, 96(24):9849-9858(2024) [pubmed]

submitter keyword: IEC, protein compelx, CF-MS

Mingxia Gao
contact affiliation	Fudan University
contact email	mxgao@fudan.edu.cn
lab head
Wei Liu
contact affiliation	Fudan University
contact email	wliu21@m.fudan.edu.cn
dataset submitter

iProX dataset URI