PXD052647

PXD052647 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic analysis of human eosinophils stimulated with NOD2 ligand and IL-5
Description	Activated eosinophils are a major cell type involved in allergic diseases. IL-5 primarily activates eosinophils and prolongs their survival. However, interactions between these cells and microorganisms are also important for further activation. NOD2 (Nucleotide-binding oligomerization domain-containing protein 2) is an intracellular pattern recognition receptor that plays a key role in the immune system. It recognizes muramyl dipeptide (MDP), a component of bacterial cell walls. The aim of this study is to clarify the role of NOD2 as a key receptor for human eosinophil activation.
HostingRepository	jPOST
AnnounceDate	2025-05-29
AnnouncementXML	Submission_2025-05-28_08:00:14.168.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jun Miyata
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; unknown modification
Instrument	LTQ Orbitrap

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-05-28 20:26:47	ID requested
⏵ 1	2025-05-28 08:00:14	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: human eosinophil, NOD2, MDP, IL-5

submitter keyword: human eosinophil, NOD2, MDP, IL-5

Contact List

Jun Miyata
lab head
Jun Miyata
contact affiliation	Keio University
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003138/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003138/