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PXD052647

PXD052647 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of human eosinophils stimulated with NOD2 ligand and IL-5
DescriptionActivated eosinophils are a major cell type involved in allergic diseases. IL-5 primarily activates eosinophils and prolongs their survival. However, interactions between these cells and microorganisms are also important for further activation. NOD2 (Nucleotide-binding oligomerization domain-containing protein 2) is an intracellular pattern recognition receptor that plays a key role in the immune system. It recognizes muramyl dipeptide (MDP), a component of bacterial cell walls. The aim of this study is to clarify the role of NOD2 as a key receptor for human eosinophil activation.
HostingRepositoryjPOST
AnnounceDate2025-05-29
AnnouncementXMLSubmission_2025-05-28_08:00:14.168.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJun Miyata
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; unknown modification
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-05-28 20:26:47ID requested
12025-05-28 08:00:14announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: human eosinophil, NOD2, MDP, IL-5
Contact List
Jun Miyata
lab head
Jun Miyata
contact affiliationKeio University
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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