PXD052564

PXD052564 is an original dataset announced via ProteomeXchange.

Title	Nucleotide metabolism-related host proteins RPB2 and UPP1 interacting with PEDV N proteins affect viral replication
Description	Porcine epidemic diarrhea virus (PEDV) is a highly pathogenic infectious disease targeting pig intestine that is widespread in the world, causing huge economic losses to pig industry. PEDV N protein is the core protein of PEDV, which locates in the cytoplasm and wraps the RNA genome of the virus to form spiral ribonucleoprotein (RNP). However, host proteins interacting with N proteins and their role in PEDV replication have not been fully elucidated. In this study, PEDV-N labeled antibodies were immunoprecipitated (Co-IP) and combined with LC-MS/MS to screen host proteins interacting with N proteins.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:43:59.782.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qiyuan Kuang
SpeciesList	scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF; Thermo Fisher Scientific instrument model

Revision	Datetime	Status	ChangeLog Entry
0	2024-05-25 23:10:47	ID requested
1	2024-06-07 03:47:55	announced
⏵ 2	2024-10-22 06:44:00	announced	2024-10-22: Updated project metadata.

10.3389/FVETS.2024.1417348;

submitter keyword: Protein interaction,Porcine epidemic diarrhea virus, N protein, UPP1, RPB2

Guihong Zhang
contact affiliation	South China Agricultural University
contact email	guihongzh@scau.edu.cn
lab head
Qiyuan Kuang
contact affiliation	South China Agricultural University
contact email	20222028015@stu.scau.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD052564

PRIDE project URI

• PRIDE
  1. PXD052564
     1. Label: PRIDE project
     2. Name: Nucleotide metabolism-related host proteins RPB2 and UPP1 interacting with PEDV N proteins affect viral replication