PXD052561

PXD052561 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Exploring Top-Down Mass Spectrometric Approaches To Probe Forest Cobra (Naja melanoleuca) Venom Proteoforms
Description	Three main top-down mass spectrometry methodologies were employed in a proof-of-concept study to characterise selected three finger toxins and phospholipase A2 toxins from the forest cobra (Naja melanoleuca) venom. The novel utility of data-independent acquisition, alternative hybrid ECD-CID fragmentation and the incorporation of cyclic ion mobility separation in a top-down proteomic workflow were explored for snake venom proteins.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:57:44.433.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ruth Wang
SpeciesList	scientific name: Naja melanoleuca; NCBI TaxID: 8643;
ModificationList	No PTMs are included in the dataset
Instrument	SELECT SERIES Cyclic IMS; Xevo G2-XS Tof

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-05-24 22:15:02	ID requested
1	2024-10-08 11:38:37	announced
⏵ 2	2024-10-22 06:57:44	announced	2024-10-22: Updated project metadata.

Publication List

10.1021/ACS.JPROTEOME.4C00486;

10.1021/ACS.JPROTEOME.4C00486;

Keyword List

submitter keyword: ECD-CID fragmentation, proteoforms, top-down proteomics, cyclic ion mobility,snake venom, data-independent acquisition

submitter keyword: ECD-CID fragmentation, proteoforms, top-down proteomics, cyclic ion mobility,snake venom, data-independent acquisition

Contact List

Tara Pukala
contact affiliation	Discipline of Physics, Chemistry and Earth Sciences, The University of Adelaide, South Australia, Australia
contact email	tara.pukala@adelaide.edu.au
lab head
Ruth Wang
contact affiliation	The University of Adelaide
contact email	crwang7796@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/09/PXD052561
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/09/PXD052561

PRIDE project URI

Repository Record List

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