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PXD052423

PXD052423 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleNew antimicrobial agents development
DescriptionWith the growing antibiotic resistance of Staphylococcus aureus, it is urgent to discover new antimicrobials to solve this problem. By bacterial growth based high-throughput screening, we identified two compounds, C218-0546 and STK848198, with effective antimicrobial activity against S. aureus. This study aims to explore the model of action of the compounds by transcriptomic analysis and other microbiological methods. The transcriptomic data would provide us information about the regulated genes, and hence help us further study the underlying antimicrobial mechanisms by the compounds.
HostingRepositoryiProX
AnnounceDate2024-05-20
AnnouncementXMLSubmission_2024-05-20_20:00:36.450.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterWei Zhang
SpeciesList scientific name: Staphylococcus aureus; NCBI TaxID: 1280;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-05-20 19:59:58ID requested
12024-05-20 20:00:36announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: S. aureus, antimicrobial, resistance
Contact List
Yong Wu
contact affiliationThe Third Xiangya Hospital of Central South University
contact emailwuyong_zn@csu.edu.cn
lab head
Wei Zhang
contact affiliationGeneticBiotech
contact emailzhangwei2039@126.com
dataset submitter
Full Dataset Link List
iProX dataset URI