PXD052389
PXD052389 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Merging molecular glue and inhibitor for degrading GSPT1 and inhibiting mTOR proteins concurrently |
| Description | U87 cells were treated with the 300 nM YB-3-17 and MLN0128 for 4 h before cell lysis. GSPT1 stood out as the most down-regulated targets. Quantitative analysis of the cells after treatment. |
| HostingRepository | iProX |
| AnnounceDate | 2024-05-17 |
| AnnouncementXML | Submission_2024-05-19_22:36:05.688.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yongbo Liu |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-05-19 22:35:20 | ID requested | |
| ⏵ 1 | 2024-05-19 22:36:06 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: dual mechanism of degrader and inhibitor，mTOR inhibition，GSPT1 degradation，glioblastoma |
Contact List
| Yu Rao | |
|---|---|
| contact affiliation | Tsinghua University |
| contact email | yrao@mail.tsinghua.edu.cn |
| lab head | |
| Yongbo Liu | |
| contact affiliation | Tsinghua University |
| contact email | liuyb19@mails.tsinghua.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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