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PXD052368

PXD052368 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe extracellular matrix (ECM) and integrin adhesion complexes (IACs) composition in DU145 prostate cancer parental and radioresistant cells
DescriptionCell adhesion to the extracellular matrix (ECM) is a critical component of malignant transformation, cancer progression, and the development of radioresistance. This mechanism of cancer cell resistance to therapy is defined as the cell adhesion mediated radioresistance (CAM-RR). There are two groups of proteins whose alteration can lead to the emergence of CAM-RR: (i) adhesion molecules (collectively called adhesome) and (ii) ECM molecules (collectively called matrisome). In order to identify proteins that mediate radioresistance, in this study we analyzed the adhesomes and matrisomes of DU145 parental and radioresistant prostate cancer cells.
HostingRepositoryPRIDE
AnnounceDate2024-07-31
AnnouncementXMLSubmission_2024-07-31_09:59:59.740.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterIvana Samarzija
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-05-18 15:38:16ID requested
12024-07-31 10:00:00announced
Publication List
10.3389/FCELL.2024.1452463;
Keyword List
submitter keyword: integrin adhesion complexes (IACs), radioresistance,Prostate cancer, extracellular matrix
Contact List
Andreja Ambriovic Ristov
contact affiliationLaboratory for Cell Biology and Signalling, Rudjer Boskovic Institute, Zagreb, Croatia
contact emailandreja.ambriovic.ristov@irb.hr
lab head
Ivana Samarzija
contact affiliationRudjer Boskovic Institute, Zagreb
contact emailivana.samarzija@irb.hr
dataset submitter
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Dataset FTP location
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PRIDE project URI
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