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PXD052358

PXD052358 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLC-MS targeting the rpL40-Lys22 spanning peptide in rpL40-immunoprecipitated KKLS human gastric cancer cell extracts
DescriptionWe identified SMYD5 (SET and MYND Domain-Containing Protein 5) physiologically methylates core ribosomal protein L40 at lysine 22 (rpL40K22me3). rpL40K22me3 depletion upon SMYD5 knockdown in GAC KKLS cells was observed by targeted-mass spectrometry of immunoprecipitated rpL40.
HostingRepositoryPRIDE
AnnounceDate2024-10-07
AnnouncementXMLSubmission_2024-10-07_13:53:27.246.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJuhyung Park
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListN6,N6,N6-trimethyl-L-lysine
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-05-17 20:42:16ID requested
12024-10-07 13:53:27announced
Publication List
10.1038/S41586-024-07718-0;
Keyword List
ProteomeXchange project tag: Cancer (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: Human, rpL40K22me3, LC-MS, GAC, gastric adenocarcinoma, rpL40 methylation, rpL40 IP, rpL40
Contact List
Or Gozani
contact affiliationDepartment of biology, Stanford University, The Gozani Lab
contact emailogozani@stanford.edu
lab head
Juhyung Park
contact affiliationStanford University
contact emailluffguy2@gmail.com
dataset submitter
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Dataset FTP location
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