PXD052338

PXD052338 is an original dataset announced via ProteomeXchange.

Title	The jumbo phage killer immune system targets early infection of nucleus-forming jumbo phages
Description	We profiled the proteomics of jumbophage phiKZ infected Pseudomonas aerugionsa cells to understand the effect of a newly discovered bacterial immune system (named jumbophage killer or Juk) on phiKZ early infection. Specifically, Juk+ and Juk- P. aeruginosa cells were infected with phiKZ at MOI 2.5. Infected cells were collected at five minutes post-infection and prepared for proteomics analysis.Â
HostingRepository	PRIDE
AnnounceDate	2025-06-16
AnnouncementXML	Submission_2025-06-15_16:10:47.788.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Frank Stein
SpeciesList	scientific name: Pseudomonas aeruginosa UCSF15-17; NCBI TaxID: 1084724;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-05-17 02:44:07	ID requested
⏵ 1	2025-06-15 16:10:48	announced

Yuping L, Guan L, Becher I, Makarova KS, Cao X, Hareendranath S, Guan J, Stein F, Yang S, Boergel A, Lapouge K, Remans K, Agard D, Savitski M, Typas A, Koonin EV, Feng Y, Bondy-Denomy J, Jumbo phage killer immune system targets early infection of nucleus-forming phages. Cell, 188(8):2127-2140.e21(2025) [pubmed]

10.1016/j.cell.2025.02.016;

submitter keyword: Jumbo bacteriophages, LC-MSMS, TMT10plex, Pseudomonas aeruginosa

Joseph Bondy-Denomy
contact affiliation	Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94403, USA Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, CA 94403, USA Innovative Genomics Institute, Berkeley, CA, USA
contact email	Joseph.Bondy-Denomy@ucsf.edu
lab head
Frank Stein
contact affiliation	EMBL
contact email	frank.stein@embl.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD052338

PRIDE project URI

• PRIDE
  1. PXD052338
     1. Label: PRIDE project
     2. Name: The jumbo phage killer immune system targets early infection of nucleus-forming jumbo phages