PXD052328
PXD052328 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Multi-omics screening of differentially expressed genes and related mechanisms of gastric neuroendocrine tumors |
| Description | This project uses transcriptome sequencing combined with proteomic analysis technology to find the mRNA and proteins differentially expressed between G-NENs and normal gastric mucosal tissues. Through bioinformatic analysis, potentially meaningful functional genes and their signaling pathways are screened, and the protein interaction network (PPI) of differentially expressed genes is constructed. Cytologically verified the function of the target genes and their regulatory pathways. By detecting the expression level of the target protein in clinical samples, the clinical application value of the target gene in G-NENs was clarified, and the possibility of serving as a molecular marker of G-NENs to judge the disease progression, treatment and prognosis was comprehensively evaluated. The ultimate goal is to discover the ultimate goal of target genes affecting the occurrence, development and prognosis of G-NENs. |
| HostingRepository | iProX |
| AnnounceDate | 2024-05-17 |
| AnnouncementXML | Submission_2024-05-16_20:44:59.592.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Meng Zhang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-05-16 20:43:51 | ID requested | |
| ⏵ 1 | 2024-05-16 20:44:59 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Multi-omics, gastric neuroendocrine neoplasm, gene ontology |
| bioinformatic analysis |
Contact List
| Shengmian Li | |
|---|---|
| contact affiliation | Division of Gastroenterology, The Fourth Hospital of Hebei Medical University |
| contact email | shengmianli2013@163.com |
| lab head | |
| Meng Zhang | |
| contact affiliation | The Fourth Hospital of Hebei Medical University |
| contact email | 327299621@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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