PXD052264
PXD052264 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | IDH1-mutant metabolite D-2-Hydroxyglutarate inhibits proliferation and sensitizes glioma to Temozolomide via down-regulating ITGB4/PI3K/AKT |
| Description | The effects of D-2HG on U251 cells by conducting a proteomic analysis |
| HostingRepository | iProX |
| AnnounceDate | 2024-05-13 |
| AnnouncementXML | Submission_2024-12-10_19:30:27.593.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Shuangmei Tong |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion; Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-05-14 18:58:21 | ID requested | |
| 1 | 2024-05-14 18:58:48 | announced | |
| ⏵ 2 | 2024-12-10 19:30:28 | announced | 2024-12-11: Update information. |
Publication List
| Tong S, Wu J, Song Y, Fu W, Yuan Y, Zhong P, Liu Y, Wang B, IDH1-mutant metabolite D-2-hydroxyglutarate inhibits proliferation and sensitizes glioma to temozolomide via down-regulating ITGB4/PI3K/AKT. Cell Death Discov, 10(1):317(2024) [pubmed] |
Keyword List
| submitter keyword: Glioma, IDH1 mutation, D-2-hydroxyglutarate, Temozolomide, ITGB4 |
Contact List
| Bin Wang | |
|---|---|
| contact affiliation | Huashan Hospital, Fudan University School of Medicine |
| contact email | hsbinwang@163.com |
| lab head | |
| Shuangmei Tong | |
| contact affiliation | Huashan Hospital, Fudan University School of Medicine |
| contact email | 18301877229@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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