PXD052242
PXD052242 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | High-fat diet alters retinal lipid composition and gene expression networks in mice |
| Description | To reveal whether a long-term HFD alters gene expression levels in the retina, we used 4D-label free mass spectrometry to quantify proteins in the whole retinas of HFM and age-mated NM. As the liver plays a crucial role in metabolism of the whole body, HFD has a huge impact on gene expression in the liver. To compare the similarities and differences in the effects of a HFD on retinal and hepatic gene regulatory networks, we also performed proteomic analyses on the livers from HFM and NM. |
| HostingRepository | iProX |
| AnnounceDate | 2024-05-14 |
| AnnouncementXML | Submission_2025-03-31_19:41:07.628.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Rong Zou |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-05-13 19:56:33 | ID requested | |
| ⏵ 1 | 2025-03-31 19:41:08 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: HFD, metabolic homeostasis, retina, cholesterol |
Contact List
| Lin Zhang | |
|---|---|
| contact affiliation | University Of Electronic Science And Technology Of China |
| contact email | zhanglin202@uestc.edu.cn |
| lab head | |
| Rong Zou | |
| contact affiliation | University Of Electronic Science And Technology Of China |
| contact email | 202121130715@std.uestc.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |




