PXD052235

PXD052235 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Protein interactions of a novel tRNA-derived small RNA
Description	Explore protein binding partners of novel tRNA (tRNA-Asp-GTC-3'tDR) in HEK293 cells via IP followed by mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2025-08-08
AnnouncementXML	Submission_2025-08-08_08:42:38.982.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Krystine Mansfield
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-05-13 15:08:17	ID requested
⏵ 1	2025-08-08 08:42:39	announced

Publication List

Li G, Sun L, Xin C, Hao T, Kharel P, Manning AC, O'Connor CL, Moore H, Lei S, Gokulnath P, Yang X, Sharma R, Garcia-Mansfield K, Pantham P, Xiao C, Wang HY, Chatterjee E, Yim S, Ren LB, Spanos M, Zhu H, Li H, Lei J, Markmann JF, Laurent LC, Rossi JJ, Akeju O, Sheng Q, Shah RV, Goddard WA, Lowe TM, Pirrotte P, Bitzer M, Ivanov P, Bonventre JV, Das S, A hypoxia-responsive tRNA-derived small RNA confers renal protection through RNA autophagy. Science, 389(6763):eadp5384(2025) [pubmed]
10.1126/science.adp5384;

Li G, Sun L, Xin C, Hao T, Kharel P, Manning AC, O'Connor CL, Moore H, Lei S, Gokulnath P, Yang X, Sharma R, Garcia-Mansfield K, Pantham P, Xiao C, Wang HY, Chatterjee E, Yim S, Ren LB, Spanos M, Zhu H, Li H, Lei J, Markmann JF, Laurent LC, Rossi JJ, Akeju O, Sheng Q, Shah RV, Goddard WA, Lowe TM, Pirrotte P, Bitzer M, Ivanov P, Bonventre JV, Das S, A hypoxia-responsive tRNA-derived small RNA confers renal protection through RNA autophagy. Science, 389(6763):eadp5384(2025) [pubmed]

10.1126/science.adp5384;

Keyword List

submitter keyword: mass spectrometry, protein binding, tRNA,human, HEK293

submitter keyword: mass spectrometry, protein binding, tRNA,human, HEK293

Contact List

Patrick Pirrotte
contact affiliation	Translational Genomic Research Institute
contact email	ppirrotte@tgen.org
lab head
Krystine Mansfield
contact affiliation	TGen
contact email	kgarcia@tgen.org
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD052235
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD052235

PRIDE project URI

Repository Record List

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