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PXD052210

PXD052210 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleGauron_PKC_timsTOFPro2_P124_VS16
DescriptionThis dataset consists of 12 raw MS files and associated peak lists and results files, acquired on a Bruker timsTOF Pro 2 operated in Data Dependent Acquisition mode. Samples were generated by Celeste Gauron. Affinity purification was performed by Laura McGary. Mass spectrometry acquisition was performed by Laura McGary. Analysis was performed by Celeste Gauron, Laura McGary, and Alexandra Newton. The files are associated with a manuscript submitted for publication by Celeste Gauron et al. The main goal of this dataset was to identify aberrant signaling mechanisms of a missense mutation in protein kinase C eta (PRKCH gene), found to be associated with families affected by Alzheimers disease. Rudolph Tanzi (tanzi@helix.mgh.harvard.edu) and Alexandra Newton (anewton@health.ucsd.edu) are the corresponding authors of the manuscript; Karen Colwill should be contacted for questions on this dataset (colwill@lunenfeld.ca)
HostingRepositoryMassIVE
AnnounceDate2025-05-16
AnnouncementXMLSubmission_2025-05-16_04:40:35.081.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterKaren Colwill
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListL-methionine sulfoxide; Acetyl
InstrumenttimsTOF Pro 2
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-05-13 04:29:27ID requested
12025-05-16 04:40:35announced
Publication List
no publication
Keyword List
submitter keyword: Proximity-dependent biotinylation, PRKCH, Alzheimer's disease
Contact List
Karen Colwill
contact affiliationLTRI
contact emailcolwill@lunenfeld.ca
lab head
Karen Colwill
contact affiliationLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
contact emailcolwill@lunenfeld.ca
dataset submitter
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MassIVE dataset URI
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v07/MSV000094742/