PXD052210

PXD052210 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Gauron_PKC_timsTOFPro2_P124_VS16
Description	This dataset consists of 12 raw MS files and associated peak lists and results files, acquired on a Bruker timsTOF Pro 2 operated in Data Dependent Acquisition mode. Samples were generated by Celeste Gauron. Affinity purification was performed by Laura McGary. Mass spectrometry acquisition was performed by Laura McGary. Analysis was performed by Celeste Gauron, Laura McGary, and Alexandra Newton. The files are associated with a manuscript submitted for publication by Celeste Gauron et al. The main goal of this dataset was to identify aberrant signaling mechanisms of a missense mutation in protein kinase C eta (PRKCH gene), found to be associated with families affected by Alzheimers disease. Rudolph Tanzi (tanzi@helix.mgh.harvard.edu) and Alexandra Newton (anewton@health.ucsd.edu) are the corresponding authors of the manuscript; Karen Colwill should be contacted for questions on this dataset (colwill@lunenfeld.ca)
HostingRepository	MassIVE
AnnounceDate	2025-05-16
AnnouncementXML	Submission_2025-05-16_04:40:35.081.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Karen Colwill
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	L-methionine sulfoxide; Acetyl
Instrument	timsTOF Pro 2

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-05-13 04:29:27	ID requested
⏵ 1	2025-05-16 04:40:35	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Proximity-dependent biotinylation, PRKCH, Alzheimer's disease

submitter keyword: Proximity-dependent biotinylation, PRKCH, Alzheimer's disease

Contact List

Karen Colwill
contact affiliation	LTRI
contact email	colwill@lunenfeld.ca
lab head
Karen Colwill
contact affiliation	Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
contact email	colwill@lunenfeld.ca
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v07/MSV000094742/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v07/MSV000094742/