PXD052210
PXD052210 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Gauron_PKC_timsTOFPro2_P124_VS16 |
Description | This dataset consists of 12 raw MS files and associated peak lists and results files, acquired on a Bruker timsTOF Pro 2 operated in Data Dependent Acquisition mode. Samples were generated by Celeste Gauron. Affinity purification was performed by Laura McGary. Mass spectrometry acquisition was performed by Laura McGary. Analysis was performed by Celeste Gauron, Laura McGary, and Alexandra Newton. The files are associated with a manuscript submitted for publication by Celeste Gauron et al. The main goal of this dataset was to identify aberrant signaling mechanisms of a missense mutation in protein kinase C eta (PRKCH gene), found to be associated with families affected by Alzheimers disease. Rudolph Tanzi (tanzi@helix.mgh.harvard.edu) and Alexandra Newton (anewton@health.ucsd.edu) are the corresponding authors of the manuscript; Karen Colwill should be contacted for questions on this dataset (colwill@lunenfeld.ca) |
HostingRepository | MassIVE |
AnnounceDate | 2025-05-16 |
AnnouncementXML | Submission_2025-05-16_04:40:35.081.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Karen Colwill |
SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
ModificationList | L-methionine sulfoxide; Acetyl |
Instrument | timsTOF Pro 2 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-05-13 04:29:27 | ID requested | |
⏵ 1 | 2025-05-16 04:40:35 | announced |
Publication List
no publication |
Keyword List
submitter keyword: Proximity-dependent biotinylation, PRKCH, Alzheimer's disease |
Contact List
Karen Colwill | |
---|---|
contact affiliation | LTRI |
contact email | colwill@lunenfeld.ca |
lab head | |
Karen Colwill | |
contact affiliation | Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital |
contact email | colwill@lunenfeld.ca |
dataset submitter |
Full Dataset Link List
MassIVE dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v07/MSV000094742/ |