PXD052111
PXD052111 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Serum Proteomic characterization in Stump-tailed macaque (Macaca arctoides) with neutralizing antibodies against Dengue virus in Thailand |
Description | The dengue virus (DENV) is a leading public health problem world wide which transmitted by mosquito in the genus Ades. DENV is a single positive-stranded RNA virus with four serotypes, including DENV1-4. Infection with each serotype may provide lifelong immunity. However, reinfection with different serotypes promotes more severe disease symptoms from antibody-dependent enhancement (ADE). DENV causes a wide spectrum of clinical manifestations in humans including asymptomatic or mild dengue fever (DF), life-threatening dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). In Southeast Asia, the increasing transmission of zoonotic diseases from animals to humans, particularly in non-human primates (NHPs), presents a significant and concerning trend. NHPs play an important role as a reservoirs of DENV transmission. In our study, the serum of wild macaques with and without neutralizing antibodies against DENV was separated to profile the proteome using proteomics and bioinformatics techniques. |
HostingRepository | jPOST |
AnnounceDate | 2025-05-08 |
AnnouncementXML | Submission_2025-05-07_08:00:06.098.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Sittiruk Roytrakul |
SpeciesList | scientific name: cellular organisms; NCBI TaxID: 131567; |
ModificationList | S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide |
Instrument | instrument |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-05-08 06:01:19 | ID requested | |
⏵ 1 | 2025-05-07 08:00:06 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Dengue virus, DENV, macaque, proteomics, antibody, serum |
Contact List
Wirasak Fungfuang | |
---|---|
lab head | |
Sittiruk Roytrakul | |
contact affiliation | BIOTEC |
dataset submitter |
Full Dataset Link List
jPOST dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003100/ |