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PXD052111

PXD052111 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSerum Proteomic characterization in Stump-tailed macaque (Macaca arctoides) with neutralizing antibodies against Dengue virus in Thailand
DescriptionThe dengue virus (DENV) is a leading public health problem world wide which transmitted by mosquito in the genus Ades. DENV is a single positive-stranded RNA virus with four serotypes, including DENV1-4. Infection with each serotype may provide lifelong immunity. However, reinfection with different serotypes promotes more severe disease symptoms from antibody-dependent enhancement (ADE). DENV causes a wide spectrum of clinical manifestations in humans including asymptomatic or mild dengue fever (DF), life-threatening dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). In Southeast Asia, the increasing transmission of zoonotic diseases from animals to humans, particularly in non-human primates (NHPs), presents a significant and concerning trend. NHPs play an important role as a reservoirs of DENV transmission. In our study, the serum of wild macaques with and without neutralizing antibodies against DENV was separated to profile the proteome using proteomics and bioinformatics techniques.
HostingRepositoryjPOST
AnnounceDate2025-05-08
AnnouncementXMLSubmission_2025-05-07_08:00:06.098.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSittiruk Roytrakul
SpeciesList scientific name: cellular organisms; NCBI TaxID: 131567;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
Instrumentinstrument
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-05-08 06:01:19ID requested
12025-05-07 08:00:06announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Dengue virus, DENV, macaque, proteomics, antibody, serum
Contact List
Wirasak Fungfuang
lab head
Sittiruk Roytrakul
contact affiliationBIOTEC
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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