PXD052066 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Whole-cell proteome analyses of prototrophic Schizosaccharomyces pombe wild-type and mug174Δ strains during vegetative growth and in G0/cellular quiescence (1 day, 7 days, or 14 days following nitrogen depletion) using liquid chromatography followed by tandem mass spectrometry (LC-MS/MS) and the label-free quantitative proteomics method. |
Description | Using a whole-cell proteome approach, we investigated the effect of the mug174+ gene deletion on the proteome during vegetative growth and G0/cellular quiescence in the fission yeast Schizosaccahromyces pombe. We revealed that (1) Mug174 ensured the protein expression from intron-containing genes during vegetative growth, and (2) the proteins involved in ribosome biogenesis were increased, whereas some of the G0 essential proteins were decreased in the absence of Mug174. The data from our proteome analyses indicated that Mug174 is essential for proper protein expression. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-17 |
AnnouncementXML | Submission_2024-10-17_05:15:01.935.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Xiaoling Deng |
SpeciesList | scientific name: Schizosaccharomyces pombe; NCBI TaxID: NCBITaxon:4896; scientific name: Schizosaccharomyces pombe 972h-; NCBI TaxID: 284812; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-05-07 03:23:59 | ID requested | |
⏵ 1 | 2024-10-17 05:15:02 | announced | |
Publication List
10.1093/nar/gkae463; |
Deng X, Yao Q, Horvath A, Jiang Z, Zhao J, Fischer T, Sugiyama T, The fission yeast ortholog of Coilin, Mug174, forms Cajal body-like nuclear condensates and is essential for cellular quiescence. Nucleic Acids Res, 52(15):9174-9192(2024) [pubmed] |
Keyword List
submitter keyword: cellular quiescence,Schizosaccharomyces pombe, G0, vegetative growth, LC-MS/MS |
Contact List
Tomoyasu Sugiyama |
contact affiliation | School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China. |
contact email | tsugiyama@shanghaitech.edu.cn |
lab head | |
Xiaoling Deng |
contact affiliation | ShanghaiTech University |
contact email | dengxl@shanghaitech.edu.cn |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD052066
- Label: PRIDE project
- Name: Whole-cell proteome analyses of prototrophic Schizosaccharomyces pombe wild-type and mug174Δ strains during vegetative growth and in G0/cellular quiescence (1 day, 7 days, or 14 days following nitrogen depletion) using liquid chromatography followed by tandem mass spectrometry (LC-MS/MS) and the label-free quantitative proteomics method.