PXD051876

PXD051876 is an original dataset announced via ProteomeXchange.

Title	Analysis of the methylation state of K510, K514 and K515 of human EZH2 within recombinant PRC2
Description	Using mass-spectrometry, we are seeking to determine the extent of methylation of EZH2 K510, K514 and K515 in the above mentioned recombinant PRC2 variants, answering the question whether recombinant mutant PRC2 is automethylated to the same or similar extent as the wt PRC2 complex.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:57:55.316.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Farnusch Kaschani
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monomethylated residue; trimethylated residue; monohydroxylated residue; dimethylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-04-30 01:27:12	ID requested
1	2024-09-10 21:00:46	announced
⏵ 2	2024-10-22 06:57:55	announced	2024-10-22: Updated project metadata.

10.1016/J.MOLCEL.2024.08.025;

submitter keyword: Polycomb Repressive Complex 2 (PRC2)

automethylation

Farnusch Kaschani
contact affiliation	Farnusch Kaschani, Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany
contact email	farnusch.kaschani@uni-due.de
lab head
Farnusch Kaschani
contact affiliation	University Duisburg-Essen
contact email	farnusch.kaschani@uni-due.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/09/PXD051876

PRIDE project URI

• PRIDE
  1. PXD051876
     1. Label: PRIDE project
     2. Name: Analysis of the methylation state of K510, K514 and K515 of human EZH2 within recombinant PRC2