PXD051869
PXD051869 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Exploring the biomarkers and mechanism of action of CHZF Capsule in treating patients with acute ischaemic stroke based on proteomics technology |
| Description | Purpose Acute ischemic stroke is characterised by high disability rate and high recurrence rate, which poses a great threat to the life and health of the nation. CHZF Capsule was developed by Ren Jixue, a national medical master, and clinical studies have confirmed that it not only promotes the recovery of neurological function in patients with cerebral infarction, reduces the disability rate, but also improves the long-term prognosis, but the target of its action is still unclear. This study reveals for the first time the target of action of CHZF capsule in the treatment of acute ischaemic stroke, which provides a direction for the study of traditional Chinese medicine compound to prevent and treat acute cerebral infarction. METHODS The aim of this study was to screen the unique differential proteins in patients with acute cerebral infarction by applying CHZF capsule. Twenty patients with acute ischemic stroke were included and classified into CHZ and DZZ according to whether CHZF capsule was applied or not. |
| HostingRepository | iProX |
| AnnounceDate | 2024-04-30 |
| AnnouncementXML | Submission_2024-04-29_22:56:39.734.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yingyue Ding |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-04-29 22:55:17 | ID requested | |
| ⏵ 1 | 2024-04-29 22:56:40 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Acute ischemic stroke, CHZF capsule, biomarkers, 4D label-free proteome quantification technology |
Contact List
| Yingyue Ding | |
|---|---|
| contact affiliation | The Affiliated Hospital of Changchun University of Traditional Chinese Medicine |
| contact email | 13578883346@163.com |
| lab head | |
| Yingyue Ding | |
| contact affiliation | The Affiliated Hospital of Changchun University of Traditional Chinese Medicine |
| contact email | 13578883346@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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