PXD051805

PXD051805 is an original dataset announced via ProteomeXchange.

Title	proteomic analysis of mitochondria-associated endoplasmic reticulum membrane in a Parkinson’s disease mouse model
Description	In subacute MPTP mouse models, Nano ultra-high performance liquid chromatography-tandem mass spectrum and bioinformatic analysis were adopted to obtain the underlying molecular data of MAM fractions, providing valuable insights into its potential role in PD pathogenesis.
HostingRepository	iProX
AnnounceDate	2024-04-26
AnnouncementXML	Submission_2025-12-31_00:30:06.818.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jin Liu
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2024-04-27 19:57:56	ID requested
⏵ 1	2025-12-31 00:30:08	announced

Liu J, Liu Y, Gao C, Pan H, Huang P, Tan Y, Chen S, The ultrastructural and proteomic analysis of mitochondria-associated endoplasmic reticulum membrane in the midbrain of a Parkinson's disease mouse model. Aging Cell, 24(4):e14436(2025) [pubmed]

submitter keyword: Parkinson’s disease, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, mitochondria-associated endoplasmic reticulum membrane, proteomics

Shengdi Chen
contact affiliation	Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
contact email	chensd@rjh.com.cn
lab head
Jin Liu
contact affiliation	Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
contact email	waddlljjlj@163.com
dataset submitter

iProX dataset URI