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PXD051709

PXD051709 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTransit to Mars: low-dose γ-irradiation (Co60) induces small hormesis effect on Limnospira indica, a component of the MELiSSA life support system for space exploration
DescriptionIn this study, two experiments using low-dose gamma irradiation (Co60, 70.4 µGy h-1 and 52.5 µGy h-1) to mimic the impact of 8-weeks of Mars transit flight of semi-continuous cultures of L. indica were performed. In the first experiment, the consecutive batches were 2 weeks long. After 2 weeks, 5% of the culture was transferred to a new flask and new medium was added. In the second experiment, the batches lasted 1 week. 25% of culture was transferred to the next run. In both approaches, the cultures were continuously illuminated (full PAR, 45 µmol photons m-2 s-1, LEDs) and shaken (120 rpm). A transient hormesis effect has been observed in the first 4 weeks of experiment 1, meaning that several growth and health parameters of the irradiated cultures increased compared to the controls in this time period. Two parameters could cause the pronounced effect of irradiation in exp. 1. Firstly, the higher variation in light and irradiation per cell ratio, caused by the different dilution schemes. Secondly, the higher irradiation dose due to the decay of the source between experiment 1 and 2.
HostingRepositoryPRIDE
AnnounceDate2025-05-06
AnnouncementXMLSubmission_2025-05-06_14:52:50.120.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD051709
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterFelice Mastroleo
SpeciesList scientific name: Limnospira indica PCC 8005; NCBI TaxID: 376219;
ModificationListNo PTMs are included in the dataset
Instrumentautoflex
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-04-24 10:19:35ID requested
12025-05-06 14:52:50announced
Publication List
Fahrion J, Gupta S, Mastroleo F, Dussap CG, Leys N, . iScience, 28(3):111891(2025) [pubmed]
10.6019/PXD051709;
10.1016/j.isci.2025.111891;
Keyword List
submitter keyword: LC-MSMS, proteomics, irradiation,cyanobacteria, arthrospira
Contact List
Natalie Leys
contact affiliationHead Microbiology Unit, SCK CEN, Belgium
contact emailnatalie.leys@sckcen.be
lab head
Felice Mastroleo
contact affiliationSCK CEN
contact emailfelice.mastroleo@sckcen.be
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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