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PXD051696

PXD051696 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic raw data for ctrl HRECs, CAPSL knockdown HRECs, and CAPSL overexpression HRECs
DescriptionThe purpose of this project is to explore the changes in signaling pathways after CAPSL knockdown and overexpression, and to identify potential downstream target genes of CAPSL along with the signaling pathways they are involved in. Ultimately elucidating the molecular mechanisms underlying CAPSL pathogenesis. HRECs were transfected with ctrl shRNA, CAPSL knockdown shRNA and LentiOE CAPSL. The cells were then collected at least 72h after transfection, and samples were then usd for proteomic analysis. After cell collection, a series of cutting-edge technologies, including protein extraction, enzyme digestion, liquid chromatography-tandem mass spectrometry, and bioinformatics analysis, were employed to investigate the quantitative proteome of the samples.
HostingRepositoryPRIDE
AnnounceDate2024-09-04
AnnouncementXMLSubmission_2024-09-04_07:33:55.687.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitter文静 刘
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-04-24 02:56:11ID requested
12024-09-04 07:33:56announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: HRECs
CAPSL
knockdown
overexpression
Contact List
Wenjing Liu
contact affiliationUniversity of Electronic Science and Technology of China
contact emailnicolewjliu@163.com
lab head
文静 刘
contact affiliationUniversity of Electronic Science and Technology of China
contact emailnicolewjliu@163.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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