PXD051481

PXD051481 is an original dataset announced via ProteomeXchange.

Title	Mucin drives human gut microbial ecological interactions in an in vitro synthetic community
Description	In this study, we created a synthetic mucin-degrading microbial community to specifically study mucin-driven ecological interactions in vitro. The synthetic community consisted of primary mucin degraders and cross-feeders. We tracked community composition and dynamics and the mucin-degrading enzymes that were produced.
HostingRepository	PRIDE
AnnounceDate	2025-03-12
AnnouncementXML	Submission_2025-03-12_05:36:35.969.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sjef Boeren
SpeciesList	scientific name: Methanobrevibacter smithii DSM 11975; NCBI TaxID: 521001; scientific name: Akkermansia muciniphila ATCC BAA-835; NCBI TaxID: 349741; scientific name: Phocaeicola vulgatus ATCC 8482; NCBI TaxID: 435590; scientific name: Desulfovibrio piger ATCC 29098; NCBI TaxID: 411464; scientific name: Roseburia intestinalis L1-82; NCBI TaxID: 536231; scientific name: Ruminococcus gnavus ATCC 29149; NCBI TaxID: 411470; scientific name: Agathobacter rectalis ATCC 33656; NCBI TaxID: 515619; scientific name: Faecalibacterium prausnitzii A2-165; NCBI TaxID: 411483; scientific name: [Ruminococcus] torques ATCC 27756; NCBI TaxID: 411460; scientific name: Blautia hydrogenotrophica DSM 10507; NCBI TaxID: 476272; scientific name: Anaerostipes caccae DSM 14662; NCBI TaxID: 411490; scientific name: Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482); NCBI TaxID: 226186; scientific name: Bacteroides caccae ATCC 43185; NCBI TaxID: 411901; scientific name: Anaerobutyricum hallii DSM 3353; NCBI TaxID: 411469; scientific name: Bacteroides fragilis (strain ATCC 25285 / NCTC 9343); NCBI TaxID: 272559;
ModificationList	S-carboxamidoethyl-L-cysteine; acetylated residue; monohydroxylated residue; deamidated residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2024-04-16 02:29:58	ID requested
⏵ 1	2025-03-12 05:36:36	announced

10.1093/glycob/cwae085;

Berkhout MD, Ioannou A, de Ram C, Boeren S, Plugge CM, Belzer C, Mucin-driven ecological interactions in an in vitro synthetic community of human gut microbes. Glycobiology, 34(12):(2024) [pubmed]

submitter keyword: Gut microbiota, mucin, ecological interactions, cross-feeding, synthetic community

Sjef Boeren
contact affiliation	Wageningen University
contact email	sjef.boeren@wur.nl
lab head
Sjef Boeren
contact affiliation	Biochemistry
contact email	sjef.boeren@wur.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD051481

PRIDE project URI

• PRIDE
  1. PXD051481
     1. Label: PRIDE project
     2. Name: Mucin drives human gut microbial ecological interactions in an in vitro synthetic community