⮝ Full datasets listing

PXD051296

PXD051296 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProducts differentially secreted from perigonadal adipose tissue of overfed mice.
DescriptionMale C57BL/6J mice were implanted with intragastric catheters that allowed direct infusion of liquid into the stomach. A control group of mice received saline through the catheter and was given free access to high-fat diet (Research Diets D12492i, 60% calories from fat) over a span of months, leading to “ad libitum obesity” (ALO). Another group of mice received a hypercaloric liquid diet through the catheter, leading to an acute-onset, “overfeeding-induced obesity” (OIO). OIO mice were also given free access to high-fat diet but did not consume it while receiving hypercaloric intragastric infusions. After 12 days of infusions, the average weights of the two groups were equal. All mice were fasted for 24 hours, after which they were sacrificed and perigonadal adipose tissue (PGAT) was dissected out. PGAT was cultured ex vivo for 6 hours, after which conditioned media was collected and submitted for proteomic profiling. All mice were age-matched and 16 weeks old at time of sacrifice. “HFD” is also used to refer to the ALO condition, while “OID” is also used to refer to the OIO condition.
HostingRepositoryPRIDE
AnnounceDate2025-02-20
AnnouncementXMLSubmission_2025-02-20_06:44:49.938.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRajesh Soni
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
Instrumenttime-of-flight
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-04-09 02:29:50ID requested
12025-02-20 06:44:50announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Adipose Tissue,Mouse, Overfeeding
Contact List
Anthony Ferrante Jr.
contact affiliationTilden-Weger-Bieler Professor of Medicine Chief of Preventive Medicine & Nutrition Columbia University
contact emailawf7@cumc.columbia.edu
lab head
Rajesh Soni
contact affiliationColumbia University Medical center
contact emailrs3869@cumc.columbia.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD051296
PRIDE project URI
Repository Record List
[ + ]