PXD051294

PXD051294 is an original dataset announced via ProteomeXchange.

Title	Products differentially secreted from perigonadal adipose tissue of db/db mice.
Description	A control group of male C57BL/6J mice were fed a 60% fat diet (Research Diets D12492i) for 8 weeks, resulting in “ad libitum obesity” (ALO). Leptin receptor-deficient B6.BKS(D)-Leprdb/J (“db/db”) male mice were fed a low-fat chow diet (PicoLab Rodent Diet 20; Purina Mills Inc). Once the average body weights of the two groups were equivalent, all mice were fasted for 24 hours, after which they were sacrificed and perigonadal adipose tissue (PGAT) was dissected out. PGAT was cultured ex vivo for 6 hours, after which conditioned media was collected and submitted for proteomic profiling. At the time of sacrifice, ALO mice were 17 weeks old and db/db mice were 10 weeks old. “HFD” is also used to refer to the ALO condition while “DB” is used to refer to the “db/db” condition.
HostingRepository	PRIDE
AnnounceDate	2025-02-23
AnnouncementXML	Submission_2025-02-23_08:11:16.328.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rajesh Soni
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Bruker Daltonics timsTOF series

Revision	Datetime	Status	ChangeLog Entry
0	2024-04-09 02:29:18	ID requested
⏵ 1	2025-02-23 08:11:16	announced

10.1016/J.CELREP.2025.115318;

submitter keyword: Adipose Tissue,Mouse, db/db

Anthony Ferrante Jr.
contact affiliation	Tilden-Weger-Bieler Professor of Medicine Chief of Preventive Medicine & Nutrition Columbia University
contact email	awf7@cumc.columbia.edu
lab head
Rajesh Soni
contact affiliation	Columbia University Medical center
contact email	rs3869@cumc.columbia.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD051294

PRIDE project URI

• PRIDE
  1. PXD051294
     1. Label: PRIDE project
     2. Name: Products differentially secreted from perigonadal adipose tissue of db/db mice.