PXD051251 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Insights into differences in the dilated cardiomyopathy phenotype in mice carrying NLS variants in RBM20 revealed by multiomics |
| Description | Global bottom-up proteomics analysis of WT and RBM20 KI variants (Rbm20 S637A and Rbm20 S639G) to establish proteomic differences. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-12-08 |
| AnnouncementXML | Submission_2025-12-07_16:12:07.739.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Eli Larson |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | phosphorylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-04-07 12:54:18 | ID requested | |
| ⏵ 1 | 2025-12-07 16:12:08 | announced | |
Publication List
| Gregorich ZR, Larson EJ, Zhang Y, Braz CU, Liu C, Ge Y, Guo W, Integrated proteomics and transcriptomics analysis reveals insights into differences in premature mortality associated with disparate pathogenic RBM20 variants. J Mol Cell Cardiol, 197():78-89(2024) [pubmed] |
| 10.1016/j.yjmcc.2024.10.013; |
Keyword List
| submitter keyword: heart,Mouse, RBM20, dilated cardiomyopathy |
Contact List
| Wei Guo |
|---|
| contact affiliation | Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison WI 53706, USA |
| contact email | wguo2@wisc.edu |
| lab head | |
| Eli Larson |
|---|
| contact affiliation | University of Wisconsin-Madison |
| contact email | ejlarson2@wisc.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD051251 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD051251
- Label: PRIDE project
- Name: Insights into differences in the dilated cardiomyopathy phenotype in mice carrying NLS variants in RBM20 revealed by multiomics
