PXD051181 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Antibodies against the mono-methylated Arginine-Glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 1 (EBNA1) identify potential cellular proteins targeted in viral transformation |
Description | The viral nuclear antigen 1 (EBNA1) of Epstein Barr (EBV) features two functionally redundant Arginine-Glycine (RG) repeats that contain symmetrically and asymmetrically di-methylated (SDMA/ADMA) and also mono-methylated (MMA) Arginine residues. We generated mouse monoclonal antibodies against the mono-methylated RG-repeat between aa 328-377. In addition to detect MMA-EBNA1, we aimed at the identification of cellular proteins that are bound to MMA-modified EBNA1 in EBV-positive Raji cells. |
HostingRepository | PRIDE |
AnnounceDate | 2025-03-05 |
AnnouncementXML | Submission_2025-03-05_08:16:51.102.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Thomas Fröhlich |
SpeciesList | scientific name: Human herpesvirus 4; NCBI TaxID: 10376; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF-X |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-04-03 09:11:59 | ID requested | |
⏵ 1 | 2025-03-05 08:16:51 | announced | |
Publication List
10.1007/s00705-024-06172-7; |
Graesser C, Nord R, Flaswinkel H, Kremmer E, Meese E, Caban KM, Fr, ö, hlich T, Gr, ä, sser FA, Hart M, Use of antibodies against Epstein-Barr virus nuclear antigen 1 for detection of cellular proteins with monomethylated arginine residues that are potentially involved in viral transformation. Arch Virol, 169(12):241(2024) [pubmed] |
Keyword List
submitter keyword: Epstein-Barr Virus,Arginine-methylation, EBNA1, mono-methyl-Arginine |
Contact List
Thomas Fröhlich |
contact affiliation | Ludwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 D-81377 München |
contact email | frohlich@genzentrum.lmu.de |
lab head | |
Thomas Fröhlich |
contact affiliation | Laboratory for Functional Genome Analysis
Gene Center Munich
Ludwig-Maximilians-Universität Munich (LMU)
Feodor-Lynen-Str. 25
81377 Munich
Germany |
contact email | frohlich@genzentrum.lmu.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD051181
- Label: PRIDE project
- Name: Antibodies against the mono-methylated Arginine-Glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 1 (EBNA1) identify potential cellular proteins targeted in viral transformation