PXD051116
PXD051116 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mining novel gene targets for improving tolerance to furfural and acetic acid in Yarrowia lipolytica using whole-genome clustered regularly interspaced short palindromic repeats interference library |
Description | In this study, a whole-genome CRISPRi library was developed in Y. lipolytica and applied for enforcing the tolerance to furfural and acetic acid. Several novel gene targets were discovered through NGS before and after screening. And to analyze the tolerance mechanism caused by transcriptional repression of the most prominent gene targets, the transcriptome and proteomics were performed. |
HostingRepository | iProX |
AnnounceDate | 2024-03-31 |
AnnouncementXML | Submission_2024-10-11_23:44:31.303.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Qianxi He |
SpeciesList | scientific name: Yarrowia lipolytica; NCBI TaxID: 4952; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-03-31 20:03:09 | ID requested | |
1 | 2024-03-31 20:03:31 | announced | |
⏵ 2 | 2024-10-11 23:44:32 | announced | 2024-10-12: Update information. |
Publication List
Fang L, Chen Y, He Q, Wang L, Duan Q, Huang C, Song H, Cao Y, Mining novel gene targets for improving tolerance to furfural and acetic acid in Yarrowia lipolytica using whole-genome CRISPRi library. Bioresour Technol, 403():130764(2024) [pubmed] |
Keyword List
submitter keyword: CRISPRi library, yarrowia lipolytica, furfural tolerance, acetic tolerance |
Contact List
Yingxiu Cao | |
---|---|
contact affiliation | Tianjin University |
contact email | caoyingxiu@tju.edu.cn |
lab head | |
Qianxi He | |
contact affiliation | Tianjin University |
contact email | a18080502576@outlook.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |