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PXD051116

PXD051116 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMining novel gene targets for improving tolerance to furfural and acetic acid in Yarrowia lipolytica using whole-genome clustered regularly interspaced short palindromic repeats interference library
DescriptionIn this study, a whole-genome CRISPRi library was developed in Y. lipolytica and applied for enforcing the tolerance to furfural and acetic acid. Several novel gene targets were discovered through NGS before and after screening. And to analyze the tolerance mechanism caused by transcriptional repression of the most prominent gene targets, the transcriptome and proteomics were performed.
HostingRepositoryiProX
AnnounceDate2024-03-31
AnnouncementXMLSubmission_2024-10-11_23:44:31.303.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterQianxi He
SpeciesList scientific name: Yarrowia lipolytica; NCBI TaxID: 4952;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-03-31 20:03:09ID requested
12024-03-31 20:03:31announced
22024-10-11 23:44:32announced2024-10-12: Update information.
Publication List
Fang L, Chen Y, He Q, Wang L, Duan Q, Huang C, Song H, Cao Y, Mining novel gene targets for improving tolerance to furfural and acetic acid in Yarrowia lipolytica using whole-genome CRISPRi library. Bioresour Technol, 403():130764(2024) [pubmed]
Keyword List
submitter keyword: CRISPRi library, yarrowia lipolytica, furfural tolerance, acetic tolerance
Contact List
Yingxiu Cao
contact affiliationTianjin University
contact emailcaoyingxiu@tju.edu.cn
lab head
Qianxi He
contact affiliationTianjin University
contact emaila18080502576@outlook.com
dataset submitter
Full Dataset Link List
iProX dataset URI