PXD051098

PXD051098 is an original dataset announced via ProteomeXchange.

Title	TMT-based proteomics of BMDMs following virus infection
Description	To identify potential regulators involved in virus-triggered innate immune response, we used tandem mass tagging (TMT)-based shotgun proteomic analysis of murine bone marrow-derived macrophages (BMDMs) following sendai virus (SeV) infection. This approach facilitated the identification and relative quantification of up- or down-regulated proteins, as evaluated by replicates. Kyoto encyclopedia of genes and genomes (KEGG) analysis indicated that proteins involved in innate immune and inflammatory responses significantly increased following SeV infection. Surprisingly, we also observed a series of proteins involved in the regulation of cell cycle and DNA damage repair process were greatly impaired after SeV infection.
HostingRepository	PRIDE
AnnounceDate	2025-04-03
AnnouncementXML	Submission_2025-04-02_19:12:18.091.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Caoqi Lei
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-29 23:33:02	ID requested
⏵ 1	2025-04-02 19:12:18	announced

Dataset with its publication pending

submitter keyword: Mus BMDMs

Caoqi Lei
contact affiliation	Wuhan University, China
contact email	caoqilei@whu.edu.cn
lab head
Caoqi Lei
contact affiliation	College of Life Sciences, Wuhan University
contact email	caoqilei@whu.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD051098

PRIDE project URI

• PRIDE
  1. PXD051098
     1. Label: PRIDE project
     2. Name: TMT-based proteomics of BMDMs following virus infection