PXD051066

PXD051066 is an original dataset announced via ProteomeXchange.

Title	The proline-rich antimicrobial peptide Api137 disrupts assembly of the large ribosomal subunit inducing immature dead-end particles
Description	The scope of the mass spectrometry approach of this study was to detect the presence or absence of bL19, bL 19-EGFP, bS20 and bS20-mCherry protein in 70S ribosome preparation from E. coli MC4100 or E. coli reporter strain (RN31). Therefore, in-gel digestion and nanoUPLC-ESI-Orbitrap-MS/MS were used.
HostingRepository	PanoramaPublic
AnnounceDate	2025-01-12
AnnouncementXML	Submission_2025-01-12_14:20:31.982.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Daniela Volke
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	Oxidation
Instrument	LTQ Orbitrap XL

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-28 10:11:12	ID requested
⏵ 1	2025-01-12 14:20:32	announced

Lauer, S.M., Gasse, J., Krizsan, A. et al. The proline-rich antimicrobial peptide Api137 disrupts large ribosomal subunit assembly and induces misfolding. Nat Commun 16, 567 (2025). https://doi.org/10.1038/s41467-025-55836-8

submitter keyword: In-Gel Digest, Api137, 70S ribosome, antimicrobial peptide

Ralf Hoffmann
contact affiliation	Universität Leipzig
contact email	ralf.hoffmann@bbz.uni-leipzig.de
lab head
Daniela Volke
contact affiliation	Universität Leipzig
contact email	daniela.volke@bbz.uni-leipzig.de
dataset submitter

Panorama Public dataset URI