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PXD051061

PXD051061 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleNEDD8 loss causes cancer vulnerability to immune checkpoint blockade in triple-negative breast cancer
DescriptionWe have blocked the expression of some genes in triple-negative breast cancer cell line, MDA-MB-231, and we want to analyse the global protein changes in knockout (KO) versus control cells.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:47:01.912.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterIrineos Papakyriacou
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
InstrumentLTQ
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-03-28 08:38:15ID requested
12024-06-23 01:27:31announced
22024-10-22 06:47:04announced2024-10-22: Updated project metadata.
Publication List
10.1038/s41467-024-47987-x;
Papakyriacou I, Kutkaite G, R, ú, bies Bed, ó, s M, Nagarajan D, Alford LP, Menden MP, Mao Y, Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer. Nat Commun, 15(1):3581(2024) [pubmed]
Keyword List
submitter keyword: Human, PD-1, triple-negative breast cancer
Contact List
Yumeng Mao
contact affiliationScience for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Sweden
contact emailyumeng.mao@scilifelab.uu.se
lab head
Irineos Papakyriacou
contact affiliationScience for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Sweden
contact emailirineos.papakyriacou@igp.uu.se
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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