PXD051061

PXD051061 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	NEDD8 loss causes cancer vulnerability to immune checkpoint blockade in triple-negative breast cancer
Description	We have blocked the expression of some genes in triple-negative breast cancer cell line, MDA-MB-231, and we want to analyse the global protein changes in knockout (KO) versus control cells.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:47:01.912.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Irineos Papakyriacou
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	LTQ

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-28 08:38:15	ID requested
1	2024-06-23 01:27:31	announced
⏵ 2	2024-10-22 06:47:04	announced	2024-10-22: Updated project metadata.

Publication List

10.1038/s41467-024-47987-x;
Papakyriacou I, Kutkaite G, R, ú, bies Bed, ó, s M, Nagarajan D, Alford LP, Menden MP, Mao Y, Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer. Nat Commun, 15(1):3581(2024) [pubmed]

10.1038/s41467-024-47987-x;

Papakyriacou I, Kutkaite G, R, ú, bies Bed, ó, s M, Nagarajan D, Alford LP, Menden MP, Mao Y, Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer. Nat Commun, 15(1):3581(2024) [pubmed]

Keyword List

submitter keyword: Human, PD-1, triple-negative breast cancer

submitter keyword: Human, PD-1, triple-negative breast cancer

Contact List

Yumeng Mao
contact affiliation	Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Sweden
contact email	yumeng.mao@scilifelab.uu.se
lab head
Irineos Papakyriacou
contact affiliation	Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Sweden
contact email	irineos.papakyriacou@igp.uu.se
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD051061
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD051061

PRIDE project URI

Repository Record List

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