PXD051061 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | NEDD8 loss causes cancer vulnerability to immune checkpoint blockade in triple-negative breast cancer |
Description | We have blocked the expression of some genes in triple-negative breast cancer cell line, MDA-MB-231, and we want to analyse the global protein changes in knockout (KO) versus control cells. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:47:01.912.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Irineos Papakyriacou |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
Instrument | LTQ |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-03-28 08:38:15 | ID requested | |
1 | 2024-06-23 01:27:31 | announced | |
⏵ 2 | 2024-10-22 06:47:04 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1038/s41467-024-47987-x; |
Papakyriacou I, Kutkaite G, R, ú, bies Bed, ó, s M, Nagarajan D, Alford LP, Menden MP, Mao Y, Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer. Nat Commun, 15(1):3581(2024) [pubmed] |
Keyword List
submitter keyword: Human, PD-1, triple-negative breast cancer |
Contact List
Yumeng Mao |
contact affiliation | Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Sweden |
contact email | yumeng.mao@scilifelab.uu.se |
lab head | |
Irineos Papakyriacou |
contact affiliation | Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Sweden |
contact email | irineos.papakyriacou@igp.uu.se |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD051061 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD051061
- Label: PRIDE project
- Name: NEDD8 loss causes cancer vulnerability to immune checkpoint blockade in triple-negative breast cancer