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PXD051023

PXD051023 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHuman conjunctival fibroblasts-LC-MS/MS
DescriptionThe underlying mechanisms of conjunctival fibrosis are complex and involve multiple factors and signaling pathway. Wnt/β-catenin signaling pathway plays an important role in organelle fibrosis. In this study, ICG-001 that inhibiting Wnt/β-catenin pathway has been applied in TGFβ1-induced fibrosis model of primary human conjunctival fibroblasts (HConFs). To verify the regulator of TGFβ1-induced conjunctival fibrosis, 4D DIA technology and proteomics analysis were used to identify the differentially expressed genes and the enrichment KEGG pathways.
HostingRepositoryPRIDE
AnnounceDate2024-05-13
AnnouncementXMLSubmission_2024-05-13_03:17:01.989.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterBiting Zhou
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-03-27 10:17:27ID requested
12024-05-13 03:17:02announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: fibrosis, 4D FastDIA,Human conjunctival fibroblasts
Contact List
Biting Zhou
contact affiliationDepartment of Ophthalmology, The First Affiliated Hospital of Fujian Medical University
contact emailzhoubiting@126.com
lab head
Biting Zhou
contact affiliationThe First Affiliation of Fujian Medical University
contact emailzhoubiting@126.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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