PXD051023

PXD051023 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Human conjunctival fibroblasts-LC-MS/MS
Description	The underlying mechanisms of conjunctival fibrosis are complex and involve multiple factors and signaling pathway. Wnt/β-catenin signaling pathway plays an important role in organelle fibrosis. In this study, ICG-001 that inhibiting Wnt/β-catenin pathway has been applied in TGFβ1-induced fibrosis model of primary human conjunctival fibroblasts (HConFs). To verify the regulator of TGFβ1-induced conjunctival fibrosis, 4D DIA technology and proteomics analysis were used to identify the differentially expressed genes and the enrichment KEGG pathways.
HostingRepository	PRIDE
AnnounceDate	2024-05-13
AnnouncementXML	Submission_2024-05-13_03:17:01.989.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Biting Zhou
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-27 10:17:27	ID requested
⏵ 1	2024-05-13 03:17:02	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: fibrosis, 4D FastDIA,Human conjunctival fibroblasts

submitter keyword: fibrosis, 4D FastDIA,Human conjunctival fibroblasts

Contact List

Biting Zhou
contact affiliation	Department of Ophthalmology, The First Affiliated Hospital of Fujian Medical University
contact email	zhoubiting@126.com
lab head
Biting Zhou
contact affiliation	The First Affiliation of Fujian Medical University
contact email	zhoubiting@126.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD051023
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD051023

PRIDE project URI

Repository Record List

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