PXD051023 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Human conjunctival fibroblasts-LC-MS/MS |
Description | The underlying mechanisms of conjunctival fibrosis are complex and involve multiple factors and signaling pathway. Wnt/β-catenin signaling pathway plays an important role in organelle fibrosis. In this study, ICG-001 that inhibiting Wnt/β-catenin pathway has been applied in TGFβ1-induced fibrosis model of primary human conjunctival fibroblasts (HConFs). To verify the regulator of TGFβ1-induced conjunctival fibrosis, 4D DIA technology and proteomics analysis were used to identify the differentially expressed genes and the enrichment KEGG pathways. |
HostingRepository | PRIDE |
AnnounceDate | 2024-05-13 |
AnnouncementXML | Submission_2024-05-13_03:17:01.989.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Biting Zhou |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-03-27 10:17:27 | ID requested | |
⏵ 1 | 2024-05-13 03:17:02 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: fibrosis, 4D FastDIA,Human conjunctival fibroblasts |
Contact List
Biting Zhou |
contact affiliation | Department of Ophthalmology, The First Affiliated Hospital of Fujian Medical University |
contact email | zhoubiting@126.com |
lab head | |
Biting Zhou |
contact affiliation | The First Affiliation of Fujian Medical University |
contact email | zhoubiting@126.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD051023
- Label: PRIDE project
- Name: Human conjunctival fibroblasts-LC-MS/MS