PXD050979

PXD050979 is an original dataset announced via ProteomeXchange.

Title	Secretome analysis of ferroptotic Pfa1 cells
Description	Pfa1 cells undergo ferroptosis upon induction of knockout of the glutathione peroxidase 4 via tamoxifen treatment. Ferroptosis is a recently discovered, iron-dependent mode of cell death, whose potency to evoke an immune response in the surrounding tissue remains to be clarified. The goal of this project is to analyze newly translated protein components in the secretome of ferroptotic Pfa1 cells in order to identify immunogenic components on the protein level via a click chemistry based approach
HostingRepository	PRIDE
AnnounceDate	2025-04-24
AnnouncementXML	Submission_2025-04-24_05:56:33.434.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Prerana Wagle
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-26 04:49:45	ID requested
⏵ 1	2025-04-24 05:56:33	announced

Dataset with its publication pending

submitter keyword: mass spectrometry, cell culture, immune response,Ferroptosis, secretome

Silvia von Karstedt
contact affiliation	Cecad Research Center Cologne/Department of Translational Genomics, Cologne University medical center, Cologne, Germany
contact email	svonkars@uni-koeln.de
lab head
Prerana Wagle
contact affiliation	CECAD Research Center
contact email	proteomics-facility@uni-koeln.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD050979

PRIDE project URI

• PRIDE
  1. PXD050979
     1. Label: PRIDE project
     2. Name: Secretome analysis of ferroptotic Pfa1 cells