PXD050949
PXD050949 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Thivierge_etal_Drosha_BioID_2024 |
| Description | This dataset consists of the files for 22 BioID samples: .wiff and .wiff.scan raw MS files, .mzML peak files, and MSPLIT results files; all acquired on TripleTOF 6600 mass spectrometers operated in Data Independent Acquisition mode (SWATH). It also includes the sequence database used for analysis and the MSPLIT spectral library which was generated from paired samples acquired in Data Dependent Acquisition (DDA) mode. All streptavidin affinity purification, mass spectrometric acquisition, and data analysis was performed by Boris Dyakov. Samples were provided by Thomas Duchaine's lab (McGill University). The files are associated with a manuscript in Cell Reports by Thivierge et al. that explores the paraspeckle-independent co-transcriptional regulation of nuclear microRNA biogenesis by SFPQ, wherein SFPQ is identified as a proximally-associated protein for DROSHA. Only the Wildtype DROSHA bait data is used in the publication, but all files used in statistical analysis are provided. Thomas Duchaine is the corresponding author of the manuscript (thomas.duchaine@mcgill.ca) Anne-Claude Gingras should be contacted for questions about this dataset (gingras@lunenfeld.ca) |
| HostingRepository | MassIVE |
| AnnounceDate | 2024-09-04 |
| AnnouncementXML | Submission_2024-09-04_17:47:39.749.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Gingras Lab |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | L-methionine sulfoxide |
| Instrument | TripleTOF 6600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-03-25 04:28:02 | ID requested | |
| ⏵ 1 | 2024-09-04 17:47:40 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: BioID, Proximity-dependent biotinylation, SFPQ, miRNA, Drosha, paraspeckles, lncRNA, nuclear exosome, RNA stability, transcription |
Contact List
| Anne-Claude Gingras | |
|---|---|
| contact affiliation | LTRI |
| contact email | gingras@lunenfeld.ca |
| lab head | |
| Gingras Lab | |
| contact affiliation | Samuel Lunenfeld Research Institute |
| contact email | gingras@mshri.on.ca |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v07/MSV000094396/ |
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