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PXD050636

PXD050636 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Palmitoylation licenses RIPK1 cytotoxicity in the TNF pathway
Description	We identified S-palmitoylation as a licensing modification for RIPK1 kinase activity in the TNF pathway. We found that DHHC5 palmitoylates RIPK1 at Cys257 residue, a process dependent on K63-linked ubiquitination of RIPK1, in response to TNF stimulation.
HostingRepository	iProX
AnnounceDate	2024-03-15
AnnouncementXML	Submission_2024-03-14_19:09:18.284.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Bing Shan
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-14 19:08:56	ID requested
⏵ 1	2024-03-14 19:09:18	announced

Publication List

Dataset with its publication pending

Keyword List

submitter keyword: palmitoylation, RIPK1,TNF

Contact List

Daichao Xu
contact affiliation	Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
contact email	xudaichao@sioc.ac.cn
lab head
Bing Shan
contact affiliation	Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
contact email	shanbing@sioc.ac.cn
dataset submitter

Full Dataset Link List

iProX dataset URI