⮝ Full datasets listing
PXD050544
PXD050544 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Multi-omics of nasopharyngeal carcinoma for precision medicine research |
| Description | In this study, we performed an integrated genomic, transcriptomic, and proteomic analysis on 240 treatment-naïve NPC cases received GP induction chemotherapy plus CCRT or CCRT alone. Genetic alterations and signatures of intratumor IgA are identified to predict survival benefit from GP induction chemotherapy, which is validated in a phase III multi-center clinical cohort. Additionally, the comprehensive multi-omic profiling reveals three molecular subtypes with distinct immunologic features and GP induction chemotherapy benefits, which implicates potential therapeutic vulnerabilities to guide precision treatment strategy. |
| HostingRepository | iProX |
| AnnounceDate | 2026-02-22 |
| AnnouncementXML | Submission_2026-02-21_18:39:08.497.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Dongxue Wang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-03-11 19:31:35 | ID requested | |
| ⏵ 1 | 2026-02-21 18:39:09 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Multi-omics, nasopharyngeal carcinoma, precision medicine, proteomics |
Contact List
| Fuchu He | |
|---|---|
| contact affiliation | Beijing Proteome Research Center |
| contact email | hefc@bmi.ac.cn |
| lab head | |
| Dongxue Wang | |
| contact affiliation | Beijing Proteome Research Center |
| contact email | wang_dongxue@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
