PXD050536

PXD050536 is an original dataset announced via ProteomeXchange.

Title	Effect of a probiotic goat milk on the hepatic proteomic profile of mice fed a high-fat diet
Description	Fermented goat milk (FGM) with Lactobacillus delbrueckii subsp. indicus CRL1447 and supplemented with different mixes of lactobacilli strains (Mix1: Limosilactobacillus fermentum CRL1446 + Lactiplantibacillus paraplantarum CRL1449 + Lactiplantibacillus paraplantarum CRL1472; Mix2: CRL1446 + CRL1449; Mix3: CRL1446 + CRL1472; and Mix4: CRL1449 + CRL1472) was administered to mice fed a high-fat diet. Proteomics data show that high-fat diet generally upregulates proteins involved in fatty acid oxidation and downregulates proteins taking part in lipid synthesis, whereas the administration of FGM+Mix3 positively modulates the hepatic proteomic profile.
HostingRepository	PRIDE
AnnounceDate	2025-06-05
AnnouncementXML	Submission_2025-06-05_07:48:37.299.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	María Antonela Marquez
SpeciesList	scientific name: Olea europaea (Common olive); NCBI TaxID: 4146; scientific name: Arachis hypogaea (Peanut); NCBI TaxID: 3818; scientific name: Brassica napus (Rape); NCBI TaxID: 3708; scientific name: Halobacterium salinarum; NCBI TaxID: 2242; scientific name: Candida albicans (Yeast); NCBI TaxID: 5476; scientific name: Equus caballus (Horse); NCBI TaxID: 9796; scientific name: Mesocricetus auratus (Golden hamster); NCBI TaxID: 10036; scientific name: Ictalurus punctatus (Channel catfish); NCBI TaxID: 7998; scientific name: Bombyx mori (Silk moth); NCBI TaxID: 7091; scientific name: Enterococcus faecalis (Streptococcus faecalis); NCBI TaxID: 1351; scientific name: Caenorhabditis elegans; NCBI TaxID: 6239; scientific name: Hepatitis C virus subtype 1a; NCBI TaxID: 31646; scientific name: Bos taurus (Bovine); NCBI TaxID: 9913; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Danio rerio (Zebrafish) (Brachydanio rerio); NCBI TaxID: 7955; scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227; scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Helicobacter pylori J99 (Campylobacter pylori J99); NCBI TaxID: 85963; scientific name: Merluccius bilinearis (Silver hake); NCBI TaxID: 79698; scientific name: Brassica oleracea var. botrytis (Cauliflower); NCBI TaxID: 3715; scientific name: Cicer arietinum (Chickpea) (Garbanzo); NCBI TaxID: 3827; scientific name: Cercopithecus aethiops (Green monkey) (Grivet); NCBI TaxID: 9534; scientific name: Heliocidaris erythrogramma (Sea urchin); NCBI TaxID: 7634; scientific name: Nicotiana tabacum (Common tobacco); NCBI TaxID: 4097; scientific name: Escherichia coli; NCBI TaxID: 562; scientific name: Macaca mulatta (Rhesus macaque); NCBI TaxID: 9544; scientific name: Dictyostelium discoideum (Slime mold); NCBI TaxID: 44689; scientific name: Gallus gallus (Chicken); NCBI TaxID: 9031; scientific name: Gadus morhua (Atlantic cod); NCBI TaxID: 8049; scientific name: Hordeum vulgare (Barley); NCBI TaxID: 4513;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-11 08:19:14	ID requested
⏵ 1	2025-06-05 07:48:37	announced

Dataset with its publication pending

submitter keyword: Obesity, Lactic acid bacteria, Probiotic, Functional food

Paola Gauffin-Cano
contact affiliation	Centro de Referencia para Lactobacilos (CERELA)-CCT NOA Sur- CONICET
contact email	pgauffin@cerela.org.ar
lab head
María Antonela Marquez
contact affiliation	Centro de Referencia para Lactobacilos (CERELA) - CCT NOA SUR - CONICET
contact email	antomarquez88@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD050536

PRIDE project URI

• PRIDE
  1. PXD050536
     1. Label: PRIDE project
     2. Name: Effect of a probiotic goat milk on the hepatic proteomic profile of mice fed a high-fat diet