PXD050478

PXD050478 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	G2 Phase Controls Binary Division of Toxoplasma gondii
Description	The current study investigates the roles of a novel essential cell cycle kinase TgCrk4. We identified this kinase aalong with its cyclin partner and demonstrated that TgCrk4 regulates processes carried out during conventional G2 phase, such as repression of chromosome re-replication and centrosome re-duplication. Accumulation of TgCyc4 in the nucleus and on the centrosomes, supported the role of TgCrk4-TgCyc4 complex as a coordinator of chromosome and centrosome cycles in T. gondii.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:47:10.218.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Clem Marsilia
SpeciesList	scientific name: Toxoplasma gondii ME49; NCBI TaxID: 508771;
ModificationList	phosphorylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-08 02:07:05	ID requested
1	2024-06-23 02:09:23	announced
⏵ 2	2024-10-22 06:47:12	announced	2024-10-22: Updated project metadata.

Publication List

Hawkins LM, Wang C, Chaput D, Batra M, Marsilia C, Awshah D, Suvorova ES, /M transition in Toxoplasma gondii. EMBO J, 43(11):2094-2126(2024) [pubmed]
10.1038/s44318-024-00095-4;

Hawkins LM, Wang C, Chaput D, Batra M, Marsilia C, Awshah D, Suvorova ES, /M transition in Toxoplasma gondii. EMBO J, 43(11):2094-2126(2024) [pubmed]

10.1038/s44318-024-00095-4;

Keyword List

submitter keyword: Toxoplasma, TgCyc4, TgCrk4, G2

submitter keyword: Toxoplasma, TgCyc4, TgCrk4, G2

Contact List

Elena Suvorova
contact affiliation	Department of Internal Medicine, Division of Infectiuos Disease and Internal Medicine, Morsani College of Medicine
contact email	essuvorova@gmail.com
lab head
Clem Marsilia
contact affiliation	University of South Florida
contact email	suvorovalab@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD050478
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD050478

PRIDE project URI

Repository Record List

[ + ]