PXD050357

PXD050357 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	KLF1-activated macrophages proteomic analysis
Description	In this project we did a proteomic analysis from iPSCs-derived macrophages with the activation of thranscription factor KLF1, upon tamoxifen induction. These macrophages are a model for the study of the erythroid island (EI) niche in adult hematopoietic tissues, such as bone marrow and spleen. We wanted to assess the upregulated proteins in macrophages upon KLF1 activation to further study the interactions between macrophages and erythroid cells whithin the EI niche.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:47:00.078.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Telma Ventura
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-05 04:44:08	ID requested
1	2024-06-23 01:35:43	announced
⏵ 2	2024-10-22 06:47:00	announced	2024-10-22: Updated project metadata.

Publication List

Ventura T, Fidanza A, Wilson MC, Ferguson DCJ, Lewis PA, May A, Taylor H, Rimmer MP, Gregory CD, Frayne J, Forrester LM, Proteomic analysis reveals a potential role for extracellular vesicles within the erythroblastic island niche. Front Mol Biosci, 11():1370933(2024) [pubmed]
10.3389/fmolb.2024.1370933;

Ventura T, Fidanza A, Wilson MC, Ferguson DCJ, Lewis PA, May A, Taylor H, Rimmer MP, Gregory CD, Frayne J, Forrester LM, Proteomic analysis reveals a potential role for extracellular vesicles within the erythroblastic island niche. Front Mol Biosci, 11():1370933(2024) [pubmed]

10.3389/fmolb.2024.1370933;

Keyword List

submitter keyword: Macrophages, Erythroid Island niche, iPSCs, Proteomics,KLF1

submitter keyword: Macrophages, Erythroid Island niche, iPSCs, Proteomics,KLF1

Contact List

Lesley Forrester
contact affiliation	Centre for Regenerative Medicine (CRM), Institute for Regeneration and Repair (IRR), University of Edinburgh
contact email	l.forrester@ed.ac.uk
lab head
Telma Ventura
contact affiliation	University of Edinburgh
contact email	tventura@ed.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD050357
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD050357

PRIDE project URI

Repository Record List

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