PXD050322

PXD050322 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Interactome of Flag-TDP-43, Flag-SUMO2-TDP-43 and Flag-4xSUMO2-TDP-43
Description	Identifications of proteins interacting with TDP-43 or linear fusions of mono- or tetra-SUMO2 with TDP-43.
HostingRepository	PRIDE
AnnounceDate	2025-09-08
AnnouncementXML	Submission_2025-09-07_16:14:37.982.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jan Keiten-Schmitz
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-04 06:57:23	ID requested
⏵ 1	2025-09-07 16:14:39	announced

Publication List

10.1038/s41589-025-01886-4;
Wagner K, Keiten-Schmitz J, Adhikari B, Patra U, Husnjak K, McNicoll F, Dormann D, M, ü, ller-McNicoll M, Tascher G, Wolf E, M, ü, ller S, Induced proximity to PML protects TDP-43 from aggregation via SUMO-ubiquitin networks. Nat Chem Biol, 21(9):1408-1419(2025) [pubmed]

10.1038/s41589-025-01886-4;

Wagner K, Keiten-Schmitz J, Adhikari B, Patra U, Husnjak K, McNicoll F, Dormann D, M, ü, ller-McNicoll M, Tascher G, Wolf E, M, ü, ller S, Induced proximity to PML protects TDP-43 from aggregation via SUMO-ubiquitin networks. Nat Chem Biol, 21(9):1408-1419(2025) [pubmed]

Keyword List

submitter keyword: TDP-43 SUMO

submitter keyword: TDP-43 SUMO

Contact List

Stefan Müller
contact affiliation	Institute of Biochemistry II University Hospital Building 75 Theodor-Stern-Kai 7 60590 Frankfurt (Main)
contact email	ste.mueller@em.uni-frankfurt.de
lab head
Jan Keiten-Schmitz
contact affiliation	Goethe University, Frankfurt am Main, Germany
contact email	keiten-schmitz@em.uni-frankfurt.de
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD050322
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD050322

PRIDE project URI

Repository Record List

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