PXD050204

PXD050204 is an original dataset announced via ProteomeXchange.

Title	The molecular mechanisms of imatinb treatment on acute lung injury in septic mice through proteomic technology
Description	A septicemia model was established by intraperitoneal injection of lipopolysaccharide (LPS), followed by tail vein injection of imatinib in the treatment group and normal saline injection in the control group. Flow cytometry was used to detect inflammatory factors, and hematoxylin staining was used to detect pathological injury to the lung tissue. TMT quantitative labeling technology was used for proteomic sequencing analysis. The main target protein was identified through bioinformatics and its expression was confirmed using western blotting.
HostingRepository	iProX
AnnounceDate	2024-02-27
AnnouncementXML	Submission_2024-02-27_18:10:55.527.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xue Liang
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-27 18:09:48	ID requested
⏵ 1	2024-02-27 18:10:55	announced

Dataset with its publication pending

submitter keyword: sepsis, acute lung injury, imatinib, proteomics

Zhenyu Li
contact affiliation	Department of Emergency, the Second Hospital of Tianjin Medical University
contact email	doctorlzy@163.com
lab head
Xue Liang
contact affiliation	Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, the Second Hospital of Tianjin Medical University
contact email	liangxue19841219@126.com
dataset submitter

iProX dataset URI