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PXD050194

PXD050194 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleScreening for variable drug responses using human iPSC cohorts
DescriptionIn this report, we describe the establishment and characterisation of a laboratory-based drug screening platform that compares drug responses between multiple hiPSC lines in the pluripotent state. The platform combines a cell painting assay advanced analytics and mass-spectrometry (MS)-based proteomic profiling to detect and explain variable drug responses.
HostingRepositoryPRIDE
AnnounceDate2026-02-09
AnnouncementXMLSubmission_2026-02-08_19:50:41.415.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHao Jiang
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-02-27 10:24:15ID requested
12026-02-08 19:50:49announced
Publication List
Platani M, Jiang H, Davidson L, Hariharan S, Doyonnas R, Lamond AI, Swedlow JR, Screening for variable drug responses using human iPSC cohorts. PLoS One, 20(5):e0323953(2025) [pubmed]
10.1371/journal.pone.0323953;
Keyword List
submitter keyword: Human, proteomics, DIA, iPSCs
Contact List
Jason R. Swedlow
contact affiliationMolecular Cell and Developmental Biology, School of Life Sciences, University of Dundee
contact emailj.r.swedlow@dundee.ac.uk
lab head
Hao Jiang
contact affiliationUniversity of Dundee
contact emailh.y.jiang@dundee.ac.uk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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