PXD050182

PXD050182 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Mechanism of phage sensing and abortion by toxin-antitoxin-chaperone systems (HDX-MS)
Description	Toxin-antitoxins (TAs) are prokaryotic two-gene systems comprised of a toxin neutralised by an antitoxin. Toxin-antitoxin-chaperone (TAC) systems additionally include a SecB-like chaperone that stabilises the antitoxin by recognising its chaperone addiction (ChAD) element. TACs have been shown to mediate antiphage defence, but the mechanisms of viral sensing and restriction are unexplored. Here we tried to find the epitope between SecB and gpV with HDX-MS.
HostingRepository	PRIDE
AnnounceDate	2024-03-14
AnnouncementXML	Submission_2024-03-14_02:26:28.648.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	kyo Coppieters
SpeciesList	scientific name: Escherichia coli BW25113; NCBI TaxID: 679895;
ModificationList	No PTMs are included in the dataset
Instrument	Synapt MS

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-27 02:46:40	ID requested
⏵ 1	2024-03-14 02:26:29	announced

Publication List

10.1101/2024.02.24.581848;

10.1101/2024.02.24.581848;

Keyword List

submitter keyword: HDX-MS

submitter keyword: HDX-MS

Contact List

Chloé Martens
contact affiliation	Chloé Martens, Ph.D Chercheuse Qualifiée - FRS.FNRS Group Leader Structure and Function of Biological Membranes - Chemistry Department chloemartenslab.com - sfmb.ulb.be Phone :+32 2 650 53 83 Université Libre de Bruxelles - Campus Plaine. Building BC, Room 1C4 110 - Boulevard du Triomphe, Accès 2 1050 Brussels - Belgium
contact email	chloe.martens@ulb.be
lab head
kyo Coppieters
contact affiliation	Université Libre de Bruxelles
contact email	coppieterskyo@hotmail.fr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/03/PXD050182
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/03/PXD050182

PRIDE project URI

Repository Record List

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