PXD050078

PXD050078 is an original dataset announced via ProteomeXchange.

Title	Cellular internalization pathways of environmentally exposed microplastic particles
Description	Microplastic particles that occur in the environment are coated with different biomolecules forming an eco-corona on the particles' surface, which could consequently lead to a specific interaction of the constituents of the eco-corona with membrane receptors. To date, it is not fully understood how strong microplastic particles with and without an eco-corona bind to cellular membranes and which underlying mechanisms are responsible for cellular internalization. Here we analyzed the protein composition of two different eco-coronas (freshwater and saltwater) by LC-MS/MS.
HostingRepository	PRIDE
AnnounceDate	2025-03-07
AnnouncementXML	Submission_2025-03-07_01:05:39.686.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Thomas Fröhlich
SpeciesList	scientific name: biofilm metagenome; NCBI TaxID: 718308;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-23 04:53:38	ID requested
⏵ 1	2025-03-07 01:05:40	announced

Ramsperger AFRM, Wieland S, Wilde MV, Fr, ö, hlich T, Kress H, Laforsch C, Cellular internalization pathways of environmentally exposed microplastic particles: Phagocytosis or macropinocytosis? J Hazard Mater, 489():137647(2025) [pubmed]

10.1016/j.jhazmat.2025.137647;

submitter keyword: eco-corona,Microplastic

Thomas Fröhlich
contact affiliation	Ludwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 D-81377 München
contact email	frohlich@genzentrum.lmu.de
lab head
Thomas Fröhlich
contact affiliation	Laboratory for Functional Genome Analysis Gene Center Munich Ludwig-Maximilians-Universität Munich (LMU) Feodor-Lynen-Str. 25 81377 Munich Germany
contact email	frohlich@genzentrum.lmu.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD050078

PRIDE project URI

• PRIDE
  1. PXD050078
     1. Label: PRIDE project
     2. Name: Cellular internalization pathways of environmentally exposed microplastic particles