PXD050064

PXD050064 is an original dataset announced via ProteomeXchange.

Title	Exosomal subgroups isolated from MSCs by tangential flow filtration combined with size exclusion chromatography reals distinct molecular properties and functions
Description	Using a tangential flow filtration and size exclusion chromatography system, the exosomes derived from human umbilical cord mesenchymal stem cells (hUC-MSCs) were purified and separated, resulting in two subgroups with different characterization. These subgroups were named S1-Exos and S2-Exos. The different exosomal subgroups were subjected to proteomic analysis using protein mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_13:13:13.461.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jing Li
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-22 23:15:27	ID requested
⏵ 1	2025-05-06 13:13:14	announced

10.1002/jev2.70029;

Liu W, Wang X, Chen Y, Yuan J, Zhang H, Jin X, Jiang Y, Cao J, Wang Z, Yang S, Wang B, Wu T, Li J, Distinct molecular properties and functions of small EV subpopulations isolated from human umbilical cord MSCs using tangential flow filtration combined with size exclusion chromatography. J Extracell Vesicles, 14(1):e70029(2025) [pubmed]

submitter keyword: biogenesis, MSC,Exosome, subgroup, function, Characterization

Jing Li
contact affiliation	State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
contact email	ljwth@njmu.edu.cn
lab head
Jing Li
contact affiliation	State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China
contact email	ljwth@njmu.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD050064

PRIDE project URI

• PRIDE
  1. PXD050064
     1. Label: PRIDE project
     2. Name: Exosomal subgroups isolated from MSCs by tangential flow filtration combined with size exclusion chromatography reals distinct molecular properties and functions