PXD050059

PXD050059 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Extended proteomes of brain organ from individual neonatal rats for understanding hypoxia–ischemia-related brain Injury and drug action.
Description	Next-generation shotgun proteomics of brain organ from individual neonatal rats suffering hypoxia-ischemia related brain injury in order to assess their response to a novel pharmaceutical drug.
HostingRepository	PRIDE
AnnounceDate	2025-10-13
AnnouncementXML	Submission_2025-10-12_18:50:05.179.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jean ARMENGAUD
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: NEWT:10116;
ModificationList	monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-22 21:05:00	ID requested
⏵ 1	2025-10-12 18:50:06	announced

Publication List

Mabondzo A, Disdier C, Bouzid A, Larbi KS, Tsintzou A, Ma, ï, za A, Kim B, Costa N, Harati R, Nguyen AL, Pruvost A, Galons H, Oumata N, Armengaud J, Knijnenburg M, Verma G, Hagberg H, Gressens P, Chen XF, Hamoudi RA, Stonestreet BS, Novel purine derivatives mitigate hypoxia ischemia related brain injury through agrin, zyxin and synaptotagmin proteins. Neurotherapeutics, 22(5):e00621(2025) [pubmed]
10.1016/j.neurot.2025.e00621;

Mabondzo A, Disdier C, Bouzid A, Larbi KS, Tsintzou A, Ma, ï, za A, Kim B, Costa N, Harati R, Nguyen AL, Pruvost A, Galons H, Oumata N, Armengaud J, Knijnenburg M, Verma G, Hagberg H, Gressens P, Chen XF, Hamoudi RA, Stonestreet BS, Novel purine derivatives mitigate hypoxia ischemia related brain injury through agrin, zyxin and synaptotagmin proteins. Neurotherapeutics, 22(5):e00621(2025) [pubmed]

10.1016/j.neurot.2025.e00621;

Keyword List

submitter keyword: drug, injury, Brain, Ischemia,Proteomics, encephalopathy, Molecular pathways, Hypoxia

submitter keyword: drug, injury, Brain, Ischemia,Proteomics, encephalopathy, Molecular pathways, Hypoxia

Contact List

Jean Armengaud
contact affiliation	CEA-Marcoule, ProGenoMIX platform, DRF-Li2D, 30207 Bagnols-sur-Ceze, France
contact email	jean.armengaud@cea.fr
lab head
Jean ARMENGAUD
contact affiliation	Li2D
contact email	jean.armengaud@cea.fr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD050059
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD050059

PRIDE project URI

Repository Record List

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