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PXD050005

PXD050005 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleStudy of Potent inhibitors for CT5-3hTERT fibroblast cell line
DescriptionData independent acquisition (DIA) mass spectrometry was used to study the potent inhibitors for cancer derived fibroblast cell line, CT5-3hTERT. The fibroblast spheroids were treated with 21 different tumor inhibitors to compare their effect in proteome in comparison to treated with DMSO.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:54:30.872.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterUjjwal Suwal
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-02-21 08:10:18ID requested
12024-08-10 13:00:40announced
22024-10-22 06:54:32announced2024-10-22: Updated project metadata.
Publication List
Xia Z, Vermeulen S, Suwal U, Rappu P, Heino J, De Vuyst F, Dedeyne S, Hendrix A, Denys H, De Wever O, Cancer-associated fibroblasts mediate resistance to neoadjuvant therapy in breast cancer. Clin Transl Med, 14(7):e1779(2024) [pubmed]
10.1002/ctm2.1779;
Keyword List
submitter keyword: DIA mass spectrometry, Inhibitors,human fibroblasts, FAIMS-Orbitrap Lumos
Contact List
Jyrki Heino
contact affiliationDepartment of Life Technologies and InFLAMES Research Flagship, University of Turku, FI-20014, Turku, Finland
contact emailjyrki.heino@utu.fi
lab head
Ujjwal Suwal
contact affiliationUniversity of Turku
contact emailujjwal.suwal@utu.fi
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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