PXD049999

PXD049999 is an original dataset announced via ProteomeXchange.

Title	Integrated cellular response of the zebrafish (Danio rerio) heart in response to temperature change
Description	Zebrafish are a tropical species of fish that inhabit streams that can fluctuate dramatically in temperature. In response to a decrease in temperature, the heart of zebrafish alters the structure of the myocardium and the expression of genes that code for proteins involved in contraction. Since very little is known about the processes supporting these changes in zebrafish, this study evaluated how the protein landscape of the ventricle changes with both an acute and a chronic decrease in temperature from 27oC to 20oC at multiple time points. this tested the hypothesis that a decrease in temperature would elicit changes in protein abundance and phosphorylation to maintain heart function. This study identified 1108, 1851, 1137, and 2325 phosphopeptides at each time point and 2052, 1656, 635, and 1530 proteins at each time point.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_07:02:02.403.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jared Shaftoe
SpeciesList	scientific name: Danio rerio (Zebrafish) (Brachydanio rerio); NCBI TaxID: 7955;
ModificationList	phosphorylated residue
Instrument	Orbitrap Exploris 240

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-21 07:02:24	ID requested
1	2024-10-15 05:38:18	announced
⏵ 2	2024-10-22 07:02:02	announced	2024-10-22: Updated project metadata.

10.1242/JEB.247522;

submitter keyword: LC-MSMS, Phosphoproteomics, cold acclimation, heart,Zebrafish, Proteomics

Todd E. Gillis
contact affiliation	Department of Integrative Biology, College of Biological Sciences, University of Guelph, Ontario, Canada
contact email	tgillis@uoguelph.ca
lab head
Jared Shaftoe
contact affiliation	University of Guelph
contact email	wjshaftoe@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/10/PXD049999

PRIDE project URI

• PRIDE
  1. PXD049999
     1. Label: PRIDE project
     2. Name: Integrated cellular response of the zebrafish (Danio rerio) heart in response to temperature change